Research/Longevity Anti Aging/Low-Dose Naltrexone (LDN)

Low-Dose Naltrexone (LDN)

compound

preliminary evidencePublic

At low doses (1.5-4.5mg), intermittently blocks opioid receptors causing upregulation. Anti-inflammatory, immune modulating, neuroprotective. Off-label for autoimmune, fibromyalgia, cancer.

Category: Longevity Anti Aging·Updated 5/19/2026

Overview Science Clinical Safety Papers Protocols Outcomes

Low-Dose Naltrexone (LDN)

At low doses (1.5-4.5mg), intermittently blocks opioid receptors causing upregulation. Anti-inflammatory, immune modulating, neuroprotective. Off-label for autoimmune, fibromyalgia, cancer.