Shilajit

Shilajit, a mineral-rich substance found in mountainous regions, has been investigated for several clinical applications, though the available evidence from controlled human trials remains limited.

Metabolic and Cardiovascular Health

The most documented clinical application involves metabolic health markers. Multiple completed trials have examined shilajit's effects on glucose control and cardiovascular parameters. One study (NCT06641596) specifically investigated the combined impact of chromium, Phyllanthus emblica, and shilajit on cardiovascular health, fitness, and weight loss during exercise and diet programs. Additional trials (NCT05887050, NCT05573607) evaluated shilajit-containing formulations for glucose control markers, though detailed results from these studies are not yet published in the peer-reviewed literature.

Exercise Performance and Muscle Function

A completed clinical trial (NCT02026414) examined the effects of PrimaVie, a purified shilajit extract, combined with exercise training on human skeletal muscle function. This represents one of the few studies specifically targeting exercise performance and muscle-related outcomes with shilajit supplementation.

Male Sexual Health

One clinical trial (NCT02794454) evaluated shilajit-containing formulations for male sexual health applications, though specific efficacy data from this study requires further publication for proper assessment.

Emerging Research Areas

Preclinical research suggests potential applications in several other areas:

• Cancer: A 2026 systematic review examined preclinical evidence for shilajit in cancer applications, though this remains at the laboratory research stage
• Osteoarthritis: Research has explored shilajit as a potential disease-modifying agent for osteoarthritis, focusing on its phenolic compounds
• Gut Health: Preliminary studies have investigated shilajit's effects on intestinal microbial groups and digestive enzyme activity

Evidence Limitations

The clinical evidence base for shilajit remains relatively thin. While several controlled trials have been completed, many results have not yet been published in peer-reviewed journals, making it difficult to assess the strength and consistency of clinical effects. The available studies often examine shilajit as part of combination formulations rather than as a standalone intervention, which complicates the interpretation of its specific therapeutic contributions.

Disclaimer: This information is for educational purposes only and should not replace professional medical advice. Consult with a healthcare provider before using shilajit for any health condition.