Ashwagandha
compound
Adaptogenic herb for stress and cortisol support. Supplement.
Updated 7/14/2026
DHEA
compound
DHEA (Dehydroepiandrosterone) is a hormone produced by the adrenal glands that serves as a precursor to male and female sex hormones. It is believed to support hormone balance, improve mood, and enhance energy levels, which can be beneficial for longevity and health optimization, especially as natural levels decline with age.
Updated 7/14/2026
Estradiol
compound
Estradiol is a form of estrogen, a key hormone in the regulation of the female reproductive system and secondary sexual characteristics. It plays a crucial role in bone density, cardiovascular health, and cognitive function, making it significant for longevity and health optimization, particularly in postmenopausal women.
Updated 7/14/2026
Estradiol Cypionate
compound
Depo-Estradiol. Long-acting estradiol ester. Injectable HRT option with ~2-week activity.
Updated 7/14/2026
HCG
compound
LH analog maintains testicular function
Updated 7/14/2026
HGH (Somatropin)
compound
HGH (Somatropin) is a synthetic form of human growth hormone used to stimulate growth, cell reproduction, and regeneration. It plays a crucial role in maintaining tissue and organ health, and its decline with age is associated with decreased vitality. While it has potential benefits for longevity and health optimization, its use is controversial due to potential side effects and ethical concerns.
Updated 7/14/2026
HRT (Female Hormone Replacement Therapy)
compound
Hormone therapy. Bioidentical HRT using estradiol, progesterone, and sometimes testosterone. Restores estrogen, progesterone, and/or testosterone; reduces menopausal symptoms; protects bone and cardiovascular health.
Updated 7/14/2026
Human Growth Hormone (HGH/Somatropin)
compound
Norditropin, Humatrope, Genotropin. 191-amino acid recombinant human growth hormone. FDA-approved for GH deficiency, Turner syndrome, and HIV lipodystrophy. Used off-label for anti-aging and body composition.
Updated 7/14/2026
IGF-1 (Mecasermin)
compound
Increlex. Recombinant human IGF-1. FDA-approved for IGF-1 deficiency in children. Anti-aging and anabolic off-label use.
Updated 7/14/2026
Maca
compound
Peruvian root for libido and energy support. Supplement.
Updated 7/14/2026
MK-677
compound
MK-677, also known as Ibutamoren, is a growth hormone secretagogue that stimulates the release of growth hormone and insulin-like growth factor 1 (IGF-1). It is primarily used to enhance muscle growth, bone density, and overall body composition, which are important for longevity and health optimization. Its ability to increase growth hormone levels without affecting cortisol levels makes it a promising compound for anti-aging purposes.
Updated 7/14/2026
Oxandrolone
compound
Anavar. Mild anabolic steroid with high anabolic:androgenic ratio. FDA-approved for muscle wasting conditions. Used for body composition and TRT augmentation.
Updated 7/14/2026
Oxytocin
compound
Bonding hormone enhances connection and orgasm
Updated 7/14/2026
Pregnenolone
compound
Pregnenolone is a precursor steroid hormone involved in the synthesis of various other hormones, including progesterone, estrogen, and testosterone. It plays a role in cognitive function, mood regulation, and stress response, making it relevant for longevity and health optimization. Its potential benefits include improved cognitive performance and mood stabilization.
Updated 7/14/2026
Progesterone (Bioidentical)
compound
Prometrium, Crinone. Bioidentical form of endogenous progesterone. FDA-approved oral micronized Prometrium. Used in HRT for women, hormone balance, and sleep improvement.
Updated 7/14/2026
Rhodiola
compound
Adaptogenic herb for stress and energy support. Supplement.
Updated 7/14/2026
Shilajit
compound
Mineral-rich substance for energy and vitality support. Supplement.
Updated 7/14/2026
Tesamorelin
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary gland to produce more growth hormone. It is primarily used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. Its potential relevance to longevity and health optimization lies in its ability to modulate growth hormone levels, which can impact body composition and metabolic health.
Updated 7/14/2026
Testosterone Cypionate
compound
Testosterone Cypionate is a synthetic form of testosterone used primarily in hormone replacement therapy to treat low testosterone levels in men. It works by supplementing the body's natural testosterone, which can improve muscle mass, bone density, and overall vitality. This compound is significant for longevity and health optimization as it can help mitigate age-related declines in testosterone, thereby supporting metabolic and sexual health.
Updated 7/14/2026
Testosterone Enanthate
compound
Delatestryl. Long-acting testosterone ester (half-life ~7-10 days). Widely used for TRT and performance. FDA-approved. IM injection.
Updated 7/14/2026
Testosterone Propionate
compound
Short-acting testosterone ester (half-life ~1-3 days). More frequent dosing required. Allows rapid adjustment. IM/SubQ injection.
Updated 7/14/2026
Testosterone Undecanoate
compound
Aveed, Jatenzo. Ultra-long-acting testosterone ester. FDA-approved as Aveed (IM, every 10 weeks) and Jatenzo (oral). Brand names: Aveed, Jatenzo.
Updated 7/14/2026
Tongkat Ali
compound
Herbal extract for male vitality support. Supplement.
Updated 7/14/2026
TRT (Testosterone Replacement Therapy)
compound
Hormone therapy. Comprehensive testosterone optimization protocol including testosterone (injectable, topical, or pellet), with ancillary medications (anastrozole, gonadorelin, HCG) to maintain full hormonal function.
Updated 7/14/2026