Adipotide (FTPP)
compound
Adipotide is a peptide designed for treating obesity by targeting white adipose tissue through a dual-domain mechanism that induces endothelial cell apoptosis. Preclinical studies indicate its effectiveness in weight reduction and metabolic improvement, although dose-dependent nephrotoxicity raises safety concerns. Formulation strategies are being explored to enhance its therapeutic potential while minimizing off-target effects.
Updated 5/19/2026
AOD-9604
compound
AOD-9604 is a synthetic peptide derived from the C-terminal region of human growth hormone, aimed at promoting lipolysis without the growth-promoting effects. Its primary application focuses on metabolic disorders and weight management, showing promise in enhancing fat oxidation and recovery in orthopedic and sports medicine. Despite favorable safety profiles, AOD-9604 remains unapproved for therapeutic use in major jurisdictions, necessitating further clinical trials to establish its efficacy.
Updated 5/20/2026
ARA-290 (Cibinetide)
compound
ARA-290, a non-erythropoietic peptide, represents a significant advancement in neuroprotective therapies, particularly for small fiber neuropathy. Engineered to activate the innate repair receptor (IRR) pathway, it offers tissue protection without stimulating red blood cells. Phase II clinical trials have shown efficacy in improving metabolic control and neuropathic symptoms among diabetic patients and individuals with sarcoidosis. With a promising safety profile and ongoing research into various therapeutic applications, ARA-290 is poised to make a considerable impact in neuropathy treatment.
Updated 5/19/2026
BAM-15
compound
BAM-15 is a novel mitochondrial uncoupler designed for targeted metabolic interventions. It functions as a protonophore, fostering controlled mitochondrial uncoupling to enhance energy expenditure while minimizing toxicity. Preclinical studies reveal its potential applications in metabolic disorders and environmental pest control, particularly against invasive aquatic species. Safety evaluations indicate a favorable therapeutic window, although further toxicological assessments are necessary.
Updated 5/19/2026
BPC-157
compound
Body Protection Compound-157. 15-amino acid peptide with remarkable tissue repair, gut healing, and anti-inflammatory effects. Derived from human gastric juice. Promotes angiogenesis and tendon/ligament healing.
Updated 5/20/2026
Bremelanotide (PT-141)
compound
PT-141, Vyleesi. Cyclic heptapeptide melanocortin receptor agonist. FDA-approved for HSDD in women (Vyleesi). Activates MC3R and MC4R in CNS to increase sexual arousal.
Updated 5/19/2026
Cerebrolysin
compound
Neurotrophic peptide complex. Porcine brain-derived peptide preparation containing neurotrophic factors. Neuroprotective, promotes neuroplasticity. Used for stroke recovery, TBI, cognitive enhancement.
Updated 5/19/2026
CJC-1295
compound
Modified GRF 1-29 with DAC modification. GHRH analog - shorter half-life (~30 min), allows more natural pulsatile GH pattern. Combined with Ipamorelin for synergistic effects.
Updated 5/20/2026
CJC-1295 (with DAC)
compound
Mod GRF 1-29 with Drug Affinity Complex. Long-acting synthetic GHRH analog with Drug Affinity Complex modification. Creates high, sustained GH release. Half-life ~8 days. Used for sustained GH elevation.
Updated 5/19/2026
CJC-1295 No DAC (Modified GRF 1-29)
compound
Mod GRF 1-29, CJC No DAC. Short-acting GHRH analog without DAC modification. Creates a high, pulsatile GH release, more natural GH stimulation. Combined with Ipamorelin for synergistic effects.
Updated 5/20/2026
Dihexa
compound
Neuroprotective hexapeptide. Synaptogenic, hepatocyte growth factor receptor agonist. Cognitive enhancement, neurogenesis. 10 million times more potent than BDNF in synapse formation.
Updated 5/19/2026
DSIP
compound
Delta Sleep-Inducing Peptide. Nonapeptide. Modulates GABA, sleep architecture, hormonal balance. Promotes delta (slow-wave) sleep, modulates hormonal rhythms.
Updated 5/19/2026
Enclomiphene
compound
Selective estrogen receptor modulator stimulates LH/FSH
Updated 5/19/2026
Epithalon (Epitalon)
compound
Synthetic tetrapeptide bioregulator derived from pineal gland extract. Activates telomerase, extends telomeres, regulates melatonin production, antioxidant. Sequence: Ala-Glu-Asp-Gly.
Updated 5/19/2026
Follistatin 315
compound
FST315. 315-amino acid glycoprotein. Inhibits myostatin and activin A. Promotes muscle growth and fat reduction. Myostatin inhibitor, anabolic.
Updated 5/19/2026
Follistatin 344
compound
Myostatin inhibitor promotes muscle growth
Updated 5/19/2026
FOXO4-DRI
compound
D-Retro-Inverso-retro-inverso peptide. Blocks FOXO4-p53 interaction, induces apoptosis in senescent cells. Senolytic, clearance of "zombie cells".
Updated 5/19/2026
GHK-Cu
compound
Copper tripeptide. GHK-Cu or Copper Peptide. Naturally occurring copper-binding tripeptide with potent regenerative, anti-aging, and wound-healing properties. Promotes skin repair, collagen synthesis, hair growth.
Updated 5/20/2026
GHRP-2
compound
Potent GHRH/ghrelin mimetic; also activates CD36 receptor for cardioprotection. GH release, muscle growth, GI-1 increase. Research peptide.
Updated 5/20/2026
GHRP-6
compound
Potent synthetic hexapeptide GH-releasing peptide. Also studied for appetite stimulation and anti-metabolic properties. GH release, appetite stimulation, muscle building, growth agonist.
Updated 5/20/2026
Gonadorelin
compound
GnRH, LHRH. Binds GnRH receptors to stimulate LH and FSH release from pituitary. TRT support, fertility. Injectable form for hormone stimulation.
Updated 5/19/2026
Hexarelin
compound
Examorelin. Potent GHRP/ghrelin mimetic; also activates CD36 receptor for cardioprotection. GH release, muscle growth, cardioprotective. Research peptide.
Updated 5/20/2026
Humanin
compound
This monograph details humanin, a 24-amino acid peptide derived from mitochondria, outlining its discovery, structure, and significant pharmacological properties. It discusses humanin's protective role in cardiovascular and renal health, its mechanisms of action through various signaling pathways, and its potential as a biomarker for diseases such as acute kidney injury and breast cancer. Additionally, ongoing clinical trials investigating its utility in fertility and chronic kidney disease suggest promising implications for personalized medicine.
Updated 5/19/2026
IGF-1 LR3
compound
IGF-1 Long R3 variant. 83-amino acid analog of IGF-1. Long-acting insulin-like growth factor with higher potency. Muscle growth, anabolism, fat loss, recovery.
Updated 5/19/2026