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Retatrutide

compound

preliminary evidencePublic

Investigational triple agonist targeting GLP-1R, GIPR, and glucagon receptor. Phase II trials show up to 24% weight loss at 48 weeks — most powerful peptide weight loss to date.

Category: Metabolic Glp1·Updated 5/19/2026

Retatrutide

Investigational triple agonist targeting GLP-1R, GIPR, and glucagon receptor. Phase II trials show up to 24% weight loss at 48 weeks — most powerful peptide weight loss to date.