Skip to content
Research/Functional Nutrition/Magnesium Citrate

Magnesium Citrate

Magnesium Citrate is a magnesium salt of citric acid that is commonly used as a dietary supplement to support magnesium levels in the body. It plays a crucial role in numerous physiological processes, including muscle and nerve function, bone health, and energy production, which are important for overall health and longevity.

Intelligence Profile

Clinical Applications

Magnesium citrate is primarily used in clinical applications as a laxative and for bowel preparation prior to medical procedures such as colonoscopy. Evidence from studies and trials highlights its utility in this area.

  1. Bowel Preparation: Magnesium citrate is part of bowel preparation regimens often combined with other agents. For instance, the study titled "Efficacy of 1 L PEG Ascorbate vs Sodium Picosulfate With Magnesium Citrate Bowel Preparations for Capsule Colonoscopy and Pan-Intestinal Capsule Endoscopy" (PMID: 41810820) supports its use for clearing the gastrointestinal tract before endoscopic procedures.

  2. Combination Formulations: Another study from the completed trial "Split Dose Pico-Salax + Bisacodyl vs. PEG Split Dose" (NCT01415687) supports its use in combination therapies for effective bowel cleansing.

Beyond bowel preparation, there are emerging areas of research exploring magnesium in broader clinical contexts, although these are not specific to magnesium citrate:

  • Inflammation and Transplantation: Magnesium supplementation has been investigated for its effect on inflammatory factors in patients undergoing allogeneic hematopoietic stem cell transplantation, although the study did not focus directly on magnesium citrate (PMID: 42366232).

  • Vascular Health: Trials investigating magnesium and vascular stiffness have been conducted, but findings specific to magnesium citrate are not well-documented (NCT03632590).

The available research does not strongly establish magnesium citrate's role beyond bowel preparation, and additional evidence would be essential to support broader clinical applications.

Disclaimer: This information is intended for educational purposes and should not be considered medical advice. Always consult a healthcare professional for personal medical concerns.

Free account required

Clinical data requires a free AXIFI account to access clinical data, safety profiles, and research papers.