Tissue Repair
Browse all research documents and products related to tissue repair.
Products with Tissue Repair
Mesenchymal Stem Cell Derived
MSC Exosomes
Exosomes derived from mesenchymal stem cells for tissue regeneration and anti-inflammatory applications.
Body Protection Compound
BPC-157
IGF-1 LR3
Antimicrobial Peptide
LL-37
Documents about Tissue Repair
Diabetic wounds struggle to heal because of ROS-mediated immune dysfunction, in which the mitochondrial metabolic reprogramming of macrophages is critical for inflammation resolution and tissue repair. Here, we innovatively combine the antioxidant astaxanthin (Ast) and the metabolic activator metformin (Met) via pH-responsive dynamic Schiff base linkages to form amphiphilic Ast-PEG-Met conjugates, which self-assemble into nanomicelles (NMs). This strategy effectively improves the solubility of A
Diabetic foot ulcer (DFU) is characterized by persistent inflammation, metabolic dysfunction, and impaired angiogenesis, leading to refractory chronic wounds. Here, we report an adhesive, metformin-loaded (1.0 mM) polyethylene glycol (PEG) based hydrogel (i.e., PEG/Met), constructed from equal volume of PEG-SG (20 wt.%) and PEG-NH2 (20 wt.%), to regulate macrophage polarization and metabolism in DFU. Density functional theory (DFT) calculations and infrared spectrum confirmed its crosslinking, y