Fisetin
compound
Fisetin is a naturally occurring flavonoid found in various fruits and vegetables, known for its potential senolytic properties. It works by selectively inducing apoptosis in senescent cells, which are cells that have stopped dividing and contribute to aging and age-related diseases. This compound is of interest for longevity and health optimization due to its ability to reduce the burden of senescent cells, potentially improving tissue function and extending healthspan.
Updated 7/14/2026
Quercetin
Quercetin is a flavonoid found in many fruits and vegetables, known for its antioxidant and anti-inflammatory properties. It is being studied for its potential role as a senolytic agent, which means it may help clear out senescent cells that contribute to aging and age-related diseases. This could be significant for longevity and health optimization by reducing inflammation and improving cellular function.
Updated 7/14/2026
Rapamycin
compound
Rapamycin is a compound that inhibits the mTOR pathway, which plays a crucial role in cell growth and aging. By modulating this pathway, rapamycin has shown potential in extending lifespan and improving healthspan in various model organisms. It is considered significant for longevity due to its ability to mimic caloric restriction and delay age-related diseases.
Updated 7/14/2026